Lesions in Puppies Surviving Infection with Canine Herpesvirus

D. H. Percy, L. E. Carmichael, D. M. Albert, J. M. King, A. M. Jonas

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Four puppies experimentally infected with canine herpesvirus (CHV) and one spontaneously infected animal, all of which survived the disease, were examined. Histologically, there were a focal granulomatous encephalitis, interstitial pneumonitis, and segmental renal necrosis with dysplasia. In the animal with naturally occurring infection there was segmental cerebellar and retinal dysplasia, and CHV antigen was demonstrated in the cerebellar cortex by fluorescence microscopy. The cerebellar and retinal dysplasia indicate that CHV can impair the differentiation of such tissues.

Original languageEnglish (US)
Pages (from-to)37-53
Number of pages17
JournalVeterinary pathology
Issue number1
StatePublished - Jan 1971
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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