TY - JOUR
T1 - Levels of serum steroids, aromatase activity, and estrogen receptors in preoptic area, hypothalamus, and amygdala of B6D2F1 male house mice that differ in the display of copulatory behavior after castration
AU - Sinchak, Kevin
AU - Roselli, Charles E.
AU - Clemens, Lynwood G.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 1996/6
Y1 - 1996/6
N2 - Most male B6D2F1 hybrid house mice continue to copulate after castration (continuers), whereas others do not (noncontinuers). Copulation in continuers appears estrogen dependent. Serum testosterone (T), 17β-estradiol (E2), and dihydrotestosterone (DHT), as well as aromatase activity (AA) and estrogen receptor (ER) levels in preoptic area (POA), hypothalamus (HYP), and amygdala (AM) were measured to determine if continuers and noncontinuers differ in estrogen physiology. In general, continuers and noncontinuers did not differ in serum steroid levels, AA, or ER levels. Castration reduced AA in the POA, HYP, and AM. Castration did not affect nuclear ER levels in the POA and HYP but reduced nuclear ER in AM. The data demonstrate that castrated B6D2F1 male mice continue to be under the influence of circulating nongonadal E2 that is important for copulation.
AB - Most male B6D2F1 hybrid house mice continue to copulate after castration (continuers), whereas others do not (noncontinuers). Copulation in continuers appears estrogen dependent. Serum testosterone (T), 17β-estradiol (E2), and dihydrotestosterone (DHT), as well as aromatase activity (AA) and estrogen receptor (ER) levels in preoptic area (POA), hypothalamus (HYP), and amygdala (AM) were measured to determine if continuers and noncontinuers differ in estrogen physiology. In general, continuers and noncontinuers did not differ in serum steroid levels, AA, or ER levels. Castration reduced AA in the POA, HYP, and AM. Castration did not affect nuclear ER levels in the POA and HYP but reduced nuclear ER in AM. The data demonstrate that castrated B6D2F1 male mice continue to be under the influence of circulating nongonadal E2 that is important for copulation.
UR - http://www.scopus.com/inward/record.url?scp=0029976969&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029976969&partnerID=8YFLogxK
U2 - 10.1037/0735-7044.110.3.593
DO - 10.1037/0735-7044.110.3.593
M3 - Article
C2 - 8889004
AN - SCOPUS:0029976969
SN - 0735-7044
VL - 110
SP - 593
EP - 602
JO - Behavioral Neuroscience
JF - Behavioral Neuroscience
IS - 3
ER -