Long-lived plasma cells: A mechanism for maintaining persistent antibody production

Mark K. Slifka; Rafi Ahmed

doi:10.1016/S0952-7915(98)80162-3

Long-lived plasma cells: A mechanism for maintaining persistent antibody production

Mark K. Slifka, Rafi Ahmed

Research output: Contribution to journal › Article › peer-review

258 Scopus citations

Abstract

Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

Original language	English (US)
Pages (from-to)	252-258
Number of pages	7
Journal	Current opinion in immunology
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/S0952-7915(98)80162-3
State	Published - Jun 1998
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/S0952-7915(98)80162-3

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title = "Long-lived plasma cells: A mechanism for maintaining persistent antibody production",

abstract = "Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.",

author = "Slifka, {Mark K.} and Rafi Ahmed",

year = "1998",

month = jun,

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journal = "Current opinion in immunology",

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T1 - Long-lived plasma cells

T2 - A mechanism for maintaining persistent antibody production

AU - Slifka, Mark K.

AU - Ahmed, Rafi

PY - 1998/6

Y1 - 1998/6

N2 - Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

AB - Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

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U2 - 10.1016/S0952-7915(98)80162-3

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M3 - Article

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AN - SCOPUS:0031861905

SN - 0952-7915

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EP - 258

JO - Current opinion in immunology

JF - Current opinion in immunology

IS - 3

ER -

Long-lived plasma cells: A mechanism for maintaining persistent antibody production

Abstract

ASJC Scopus subject areas

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