Long-Term Depression (LTD): Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms

C. Lüscher; M. Frerking

doi:10.1016/B978-008045046-9.01205-5

Long-Term Depression (LTD): Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms

C. Lüscher, M. Frerking

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Long-term depression (LTD) of excitatory synaptic transmission represents a mechanism by which synapses can undergo an activity-dependent weakening of their strength. There are at least two broad classes of LTD, distinguished by the glutamate receptor that is required for LTD induction, which may be either of the NMDA (NMDAR) or metabotropic (mGluR) type. For this article we therefore distinguish NMDAR-LTD from mGluR-LTD and present contrasting properties for their induction, expression, and maintenance.

Original language	English (US)
Title of host publication	Encyclopedia of Neuroscience
Publisher	Elsevier Ltd
Pages	527-532
Number of pages	6
ISBN (Print)	9780080450469
DOIs	https://doi.org/10.1016/B978-008045046-9.01205-5
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1016/B978-008045046-9.01205-5

Cite this

@inbook{cd06cc69a8f6420598820bf8fd92422a,

title = "Long-Term Depression (LTD): Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms",

abstract = "Long-term depression (LTD) of excitatory synaptic transmission represents a mechanism by which synapses can undergo an activity-dependent weakening of their strength. There are at least two broad classes of LTD, distinguished by the glutamate receptor that is required for LTD induction, which may be either of the NMDA (NMDAR) or metabotropic (mGluR) type. For this article we therefore distinguish NMDAR-LTD from mGluR-LTD and present contrasting properties for their induction, expression, and maintenance.",

author = "C. L{\"u}scher and M. Frerking",

year = "2009",

doi = "10.1016/B978-008045046-9.01205-5",

language = "English (US)",

isbn = "9780080450469",

pages = "527--532",

booktitle = "Encyclopedia of Neuroscience",

publisher = "Elsevier Ltd",

}

TY - CHAP

T1 - Long-Term Depression (LTD)

T2 - Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms

AU - Lüscher, C.

AU - Frerking, M.

PY - 2009

Y1 - 2009

N2 - Long-term depression (LTD) of excitatory synaptic transmission represents a mechanism by which synapses can undergo an activity-dependent weakening of their strength. There are at least two broad classes of LTD, distinguished by the glutamate receptor that is required for LTD induction, which may be either of the NMDA (NMDAR) or metabotropic (mGluR) type. For this article we therefore distinguish NMDAR-LTD from mGluR-LTD and present contrasting properties for their induction, expression, and maintenance.

AB - Long-term depression (LTD) of excitatory synaptic transmission represents a mechanism by which synapses can undergo an activity-dependent weakening of their strength. There are at least two broad classes of LTD, distinguished by the glutamate receptor that is required for LTD induction, which may be either of the NMDA (NMDAR) or metabotropic (mGluR) type. For this article we therefore distinguish NMDAR-LTD from mGluR-LTD and present contrasting properties for their induction, expression, and maintenance.

UR - http://www.scopus.com/inward/record.url?scp=84882891119&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84882891119&partnerID=8YFLogxK

U2 - 10.1016/B978-008045046-9.01205-5

DO - 10.1016/B978-008045046-9.01205-5

M3 - Chapter

AN - SCOPUS:84882891119

SN - 9780080450469

SP - 527

EP - 532

BT - Encyclopedia of Neuroscience

PB - Elsevier Ltd

ER -

Long-Term Depression (LTD): Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this