Abstract
Two pediatric patients with diffuse pontine tumors underwent MR spectroscopic imaging pre- and postradiation. Choline/creatine (Cho/Cr) and Cho/N-acetylaspartate (NAA) ratios were elevated before treatment, with no MR imaging contrast enhancement. These ratios were further elevated at 2 posttreatment follow-up studies, despite signs of excellent clinical improvement at initial follow-up. This study suggests that MR spectroscopic imaging is more specific in assessing the aggressiveness of diffuse pontine tumors than conventional MR imaging and can serve as a valuable tool in early prognostication.
Original language | English (US) |
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Pages (from-to) | 806-809 |
Number of pages | 4 |
Journal | American Journal of Neuroradiology |
Volume | 27 |
Issue number | 4 |
State | Published - Apr 2006 |
Externally published | Yes |
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology