Malignancy does not dictate the hypercoagulable state following liver resection

Nicole Gordon, Gordon Riha, Kevin Billingsley, Martin Schreiber

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Background A hypercoagulable state following intra-abdominal malignant resections has been reported. Whether this is because of the operation or the malignancy, a known cause of hypercoagulability, remains unclear. We determined if malignancy status affected the coagulation profile following liver resection by assessing perioperative thromboelastogram (TEG) values. Methods Retrospective review of prospectively collected TEG values in patients who received a liver resection was conducted. Values among patients with benign or malignant disease were compared. Results Fourteen and 63 patients were resected for benign and malignant disease, respectively. No significant differences in TEG values existed between the groups. Combining the groups, patients developed a relative hypercoagulable state postoperatively with decreased R-times (P <.05), although median values remained within the normal range. Conclusion Following liver resection, no differences in TEG values existed between patients with benign and malignant disease; the relative hypercoagulable state is more likely driven by postoperative coagulopathy rather than the malignancy status of the patient.

Original languageEnglish (US)
Pages (from-to)870-874
Number of pages5
JournalAmerican journal of surgery
Issue number5
StatePublished - May 1 2015


  • Benign
  • Hypercoagulable
  • Liver
  • Malignancy
  • TEG
  • Thromboelastography

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Malignancy does not dictate the hypercoagulable state following liver resection'. Together they form a unique fingerprint.

Cite this