Massive verapamil ingestion: A report of two cases and a review of the literature

B. Zane Horowitz, Kenneth J. Rhee

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


This report describes two patients who were victims of massive verapamil ingestion and then reviews the available literature. Because verapamil blocks the slow calcium channels of the heart and blood vessels, the use of calcium as a treatment would be logical. In the two cases reported here, calcium was only transiently effective in maintaining cardiac output and blood pressure. Several other agents were then used and most were ineffective. This is similar to experience reported in the literature that suggests that no single agent is capable of reversing verapamil's negative inotropic, dromotropic, chronotropic, and vascular smooth muscle effects.

Original languageEnglish (US)
Pages (from-to)624-631
Number of pages8
JournalAmerican Journal of Emergency Medicine
Issue number6
StatePublished - Nov 1989
Externally publishedYes


  • Verapamil
  • calcium channel blockers

ASJC Scopus subject areas

  • Emergency Medicine


Dive into the research topics of 'Massive verapamil ingestion: A report of two cases and a review of the literature'. Together they form a unique fingerprint.

Cite this