@article{02a7eac120aa44ceac357d7a1ffb3245,
title = "Molecular diagnosis: Implications for ophthalmology",
abstract = "The effort to subdivide diseases and to individualize therapies based on characteristics of the patient has been labeled precision medicine. Jameson and Longo define precision medicine as {"}treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations{"} (Jameson and Longo, 2015). We illustrate how molecular diagnosis can be applied to orbital inflammatory disease to achieve the goals of precision medicine.",
keywords = "Granulomatosis with polyangiitis, Molecular diagnosis, Nonspecific orbital inflammatory disease, Sarcoidosis, Thyroid eye disease, Transcriptomics",
author = "Rosenbaum, {James T.} and Sibley, {Cailin H.} and Dongseok Choi and Harrington, {Christina A.} and Planck, {Stephen R.}",
note = "Funding Information: The authors are grateful for funding support from the National Eye Institute (Grants EY020249 and P30 EY 010572 ), and funding from the Stan and Madelle Rosenfeld Family Trust , the William and Mary Bauman Foundation , and Research to Prevent Blindness , New York. This work would not be possible without the efforts of the Orbital Inflammatory Disease Consortium which includes David J Wilson, Hans Grossniklaus, Roger Dailey, John Ng, Eric Steele Craig Czyz, Jill Foster, David Tse, Chris Alabiad, Sander Dubovy, Prashant Parekh, Gerald Harris, Michael Kazim, Payal Patel, Valerie White, Peter Dolman, Bobby Korn, Don Kikkawa, Deepak Edward, Hind Alkatan, Hailah Al-Hussain, R. Patrick Yeatts, Dinesh Selva D, and Patrick Stauffer. Publisher Copyright: {\textcopyright} 2015 Published by Elsevier Ltd.",
year = "2016",
month = jan,
day = "1",
doi = "10.1016/j.preteyeres.2015.11.001",
language = "English (US)",
volume = "50",
pages = "25--33",
journal = "Progress in Retinal Research",
issn = "1350-9462",
publisher = "Elsevier Limited",
}