Molecular machinery of auditory and vestibular transduction

Peter G. Gillespie

doi:10.1016/0959-4388(95)80004-2

Molecular machinery of auditory and vestibular transduction

Peter G. Gillespie

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na⁺ channel family.

Original language	English (US)
Pages (from-to)	449-455
Number of pages	7
Journal	Current Opinion in Neurobiology
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/0959-4388(95)80004-2
State	Published - Aug 1995
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0959-4388(95)80004-2

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title = "Molecular machinery of auditory and vestibular transduction",

abstract = "The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.",

author = "Gillespie, {Peter G.}",

year = "1995",

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PY - 1995/8

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N2 - The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.

AB - The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.

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U2 - 10.1016/0959-4388(95)80004-2

DO - 10.1016/0959-4388(95)80004-2

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ER -

Molecular machinery of auditory and vestibular transduction

Abstract

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