TY - JOUR
T1 - Moving beyond the momentum
T2 - Innovative approaches to clinical trial implementation
AU - Eng, Cathy
AU - Chen, Emerson Y.
AU - Rogers, Jane
AU - Lewis, Mark
AU - Strosberg, Jonathan
AU - Thota, Ramya
AU - Krishnamurthi, Smitha
AU - Oberstein, Paul
AU - Govindarajan, Rang
AU - Buchschacher, Gary
AU - Patel, Sandip
AU - Sohal, Davendra
AU - Al-Toubah, Taymeyah
AU - Philip, Philip
AU - Dasari, Arvind
AU - Kennecke, Hagan
AU - Stein, Stacey
N1 - Publisher Copyright:
Copyright © 2021 American Society of Clinical Oncology. All rights reserved
PY - 2021/10/1
Y1 - 2021/10/1
N2 - Despite efforts to enhance enrollment and the merger of national cooperative groups,, 5% of patients with cancer will enroll into a clinical trial. Additionally, clinical trials are affected by a lack of diversity inclusive of minority patients, rural residents, or low-income individuals. COVID-19 further exacerbated known barriers of reduced physician-patient interaction, physician availability, trial activation and enrollment, financial resources, and capacity for conducting research. Based on the cumulative insight of academic and community clinical researchers, we have created a white paper identifying existing challenges in clinical trial conduct and have provided specific recommendations of sustainable modifications to improve efficiency in the activation and conduct of clinical trials with an overarching goal of providing improved access and care to our patients with cancer.
AB - Despite efforts to enhance enrollment and the merger of national cooperative groups,, 5% of patients with cancer will enroll into a clinical trial. Additionally, clinical trials are affected by a lack of diversity inclusive of minority patients, rural residents, or low-income individuals. COVID-19 further exacerbated known barriers of reduced physician-patient interaction, physician availability, trial activation and enrollment, financial resources, and capacity for conducting research. Based on the cumulative insight of academic and community clinical researchers, we have created a white paper identifying existing challenges in clinical trial conduct and have provided specific recommendations of sustainable modifications to improve efficiency in the activation and conduct of clinical trials with an overarching goal of providing improved access and care to our patients with cancer.
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U2 - 10.1200/OP.20.00701
DO - 10.1200/OP.20.00701
M3 - Review article
C2 - 33534616
AN - SCOPUS:85109142797
SN - 2688-1527
VL - 17
SP - 607
EP - 614
JO - JCO Oncology Practice
JF - JCO Oncology Practice
IS - 10
ER -