Multifunctional catheters combining intracardiac ultrasound imaging and electrophysiology sensing

Douglas N. Stephens, Jonathan Cannata, Ruibin Liu, Jian Zhong Zhao, K. Kirk Shung, Hien Nguyen, Raymond Chia, Aaron Dentinger, Douglas Wildes, Kai E. Thomenius, Aman Mahajan, Kalyanam Shivkumar, Kang Kim, Matthew O'Donnell, Amin Nikoozadeh, Omer Oralkan, Pierre T. Khuri-Yakub, David J. Sahn

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


A family of 3 multifunctional intracardiac imaging and electrophysiology (EP) mapping catheters has been in development to help guide diagnostic and therapeutic intracardiac EP procedures. The catheter tip on the first device includes a 7.5 MHz, 64-element, side-looking phased array for high resolution sector scanning. The second device is a forward-looking catheter with a 24-element 14 MHz phased array. Both of these catheters operate on a commercial imaging system with standard software. Multiple EP mapping sensors were mounted as ring electrodes near the arrays for electrocardiographic synchronization of ultrasound images and used for unique integration with EP mapping technologies. To help establish the catheters' ability for integration with EP interventional procedures, tests were performed in vivo in a porcine animal model to demonstrate both useful intracardiac echocardiographic (ICE) visualization and simultaneous 3-D positional information using integrated electroanatomical mapping techniques. The catheters also performed well in high frame rate imaging, color now imaging, and strain rate imaging of atrial and ventricular structures. The companion paper of this work discusses the catheter design of the side-looking catheter with special attention to acoustic lens design. The third device in development is a 10 MHz forward-looking ring array that is to be mounted at the distal tip of a 9F catheter to permit use of the available catheter lumen for adjunctive therapy tools.

Original languageEnglish (US)
Article number4559656
Pages (from-to)1570-1581
Number of pages12
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Issue number7
StatePublished - Jul 2008
Externally publishedYes

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering


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