Myopericarditis in a pregnant woman with acute promyelocytic leukemia

Andrew Oehler, Shimoli Shah

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Acute promyelocytic leukemia (APL) is a form of acute leukemia with a characteristic translocation, t(15;17), and is considered a hematologic emergency, typically treated with all-trans retinoic acid and an anthracycline. We present the case of a young, gravid woman who was diagnosed with APL in the third trimester, initiated typical treatment, and suffered uncommon cardiac complications.<. Learning objective: Myopericarditis is not a side effect often encountered in the management of acute promyelocytic leukemia with alpha t-retinoic acid, and its mechanism is incompletely understood but possibly related to the differentiation syndrome. This complication can be effectively treated with systemic glucocorticoids, supportive care, and withdrawal of the offending agent, even in the pregnant population>.

Original languageEnglish (US)
Pages (from-to)200-203
Number of pages4
JournalJournal of Cardiology Cases
Issue number5
StatePublished - Nov 1 2014
Externally publishedYes


  • Acute promyelocytic leukemia
  • Differentiation syndrome
  • Myopericarditis
  • Pregnancy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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