TY - JOUR
T1 - Neurological patients confronting climate change
T2 - A potential role for the glymphatic system and sleep
AU - Reis, Jacques
AU - Buguet, Alain
AU - Radomski, Manny
AU - Stella, Alex Buoite
AU - Vásquez, Teresa Corona
AU - Spencer, Peter S.
N1 - Publisher Copyright:
© 2024 Elsevier B.V.
PY - 2024/3/15
Y1 - 2024/3/15
N2 - Interest in the health consequences of climate change (global warming, heatwaves) has increased in the neurological community. This review addresses the impact of elevated ambient temperatures and heatwaves on patients with neurological and mental health disorders, including multiple sclerosis, synucleinopathies, dementia, epilepsies, mental health, and stroke. Patients with such conditions are highly vulnerable during heatwaves because of functional disorders affecting sleep, thermoregulation, autonomic system reactivity, mood, and cognitive ability. Several medications may also increase the risk of heatstroke. Special attention is devoted to the involvement of common underlying mechanisms, such as sleep and the glymphatic system. Disease prevention and patient care during heatwaves are major issues for caregivers. Beyond the usual recommendations for individuals, we favor artificially induced acclimation to heat, which provides preventive benefits with proven efficacy for healthy adults.
AB - Interest in the health consequences of climate change (global warming, heatwaves) has increased in the neurological community. This review addresses the impact of elevated ambient temperatures and heatwaves on patients with neurological and mental health disorders, including multiple sclerosis, synucleinopathies, dementia, epilepsies, mental health, and stroke. Patients with such conditions are highly vulnerable during heatwaves because of functional disorders affecting sleep, thermoregulation, autonomic system reactivity, mood, and cognitive ability. Several medications may also increase the risk of heatstroke. Special attention is devoted to the involvement of common underlying mechanisms, such as sleep and the glymphatic system. Disease prevention and patient care during heatwaves are major issues for caregivers. Beyond the usual recommendations for individuals, we favor artificially induced acclimation to heat, which provides preventive benefits with proven efficacy for healthy adults.
KW - Climate change
KW - Glymphatic system
KW - Neurological disorders
KW - Sleep
KW - Vulnerability
UR - http://www.scopus.com/inward/record.url?scp=85183977423&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85183977423&partnerID=8YFLogxK
U2 - 10.1016/j.jns.2024.122900
DO - 10.1016/j.jns.2024.122900
M3 - Article
C2 - 38310733
AN - SCOPUS:85183977423
SN - 0022-510X
VL - 458
JO - Journal of the neurological sciences
JF - Journal of the neurological sciences
M1 - 122900
ER -