No fits at Uffizi: Fatal forty DDI: Phenytoin, cyclosporine, CYP3A4

Michael P. Hutchens; Christine M. Formea

doi:10.1007/978-1-4614-7495-1_157

No fits at Uffizi: Fatal forty DDI: Phenytoin, cyclosporine, CYP3A4

Michael P. Hutchens, Christine M. Formea

Anesthesiology and Perioperative Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses a pharmacokinetic interaction between cyclosporine and phenytoin, leading to organ rejection. Cyclosporin is a cytochrome P450 3A4 substrate and phenytoin is a 3A4 inducer.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	705-707
Number of pages	3
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_157
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_157

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title = "No fits at Uffizi: Fatal forty DDI: Phenytoin, cyclosporine, CYP3A4",

abstract = "This case discusses a pharmacokinetic interaction between cyclosporine and phenytoin, leading to organ rejection. Cyclosporin is a cytochrome P450 3A4 substrate and phenytoin is a 3A4 inducer.",

author = "Hutchens, {Michael P.} and Formea, {Christine M.}",

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PB - Springer New York

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No fits at Uffizi: Fatal forty DDI: Phenytoin, cyclosporine, CYP3A4

Abstract

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