Normal arterial blood pressure in the nephrectomized fetal lamb

Nancy D. Binder; Debra F. Anderson; D. Mark Potter; Kent L. Thornburg; J. J. Faber

doi:10.1159/000241575

Normal arterial blood pressure in the nephrectomized fetal lamb

Nancy D. Binder, Debra F. Anderson, D. Mark Potter, Kent L. Thornburg, J. J. Faber

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Arterial blood pressures in 18 lambs who had been nephrectomized 3–24 days before were not significantly different from those of 26 control fetuses or from those of control fetuses in the literature. Plasma renin activities were below the detection level of our assay. The nephrectomized fetuses continued to grow according to a variety of indices. We concluded that neither the kidney nor the renin angiotensin system are necessary for the long-term regulation of fetal blood pressure, probably because of their inability to affect placental exchange of water and electrolytes.

Original language	English (US)
Pages (from-to)	50-58
Number of pages	9
Journal	Neonatology
Volume	42
Issue number	1-2
DOIs	https://doi.org/10.1159/000241575
State	Published - 1982
Externally published	Yes

Keywords

Fetal growth
Nonrenal regulation of blood pressure
Placental water exchange
Plasma renin activity

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Biology

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10.1159/000241575

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title = "Normal arterial blood pressure in the nephrectomized fetal lamb",

abstract = "Arterial blood pressures in 18 lambs who had been nephrectomized 3–24 days before were not significantly different from those of 26 control fetuses or from those of control fetuses in the literature. Plasma renin activities were below the detection level of our assay. The nephrectomized fetuses continued to grow according to a variety of indices. We concluded that neither the kidney nor the renin angiotensin system are necessary for the long-term regulation of fetal blood pressure, probably because of their inability to affect placental exchange of water and electrolytes.",

keywords = "Fetal growth, Nonrenal regulation of blood pressure, Placental water exchange, Plasma renin activity",

author = "Binder, {Nancy D.} and Anderson, {Debra F.} and {Mark Potter}, D. and Thornburg, {Kent L.} and Faber, {J. J.}",

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AU - Binder, Nancy D.

AU - Anderson, Debra F.

AU - Mark Potter, D.

AU - Thornburg, Kent L.

AU - Faber, J. J.

PY - 1982

Y1 - 1982

N2 - Arterial blood pressures in 18 lambs who had been nephrectomized 3–24 days before were not significantly different from those of 26 control fetuses or from those of control fetuses in the literature. Plasma renin activities were below the detection level of our assay. The nephrectomized fetuses continued to grow according to a variety of indices. We concluded that neither the kidney nor the renin angiotensin system are necessary for the long-term regulation of fetal blood pressure, probably because of their inability to affect placental exchange of water and electrolytes.

AB - Arterial blood pressures in 18 lambs who had been nephrectomized 3–24 days before were not significantly different from those of 26 control fetuses or from those of control fetuses in the literature. Plasma renin activities were below the detection level of our assay. The nephrectomized fetuses continued to grow according to a variety of indices. We concluded that neither the kidney nor the renin angiotensin system are necessary for the long-term regulation of fetal blood pressure, probably because of their inability to affect placental exchange of water and electrolytes.

KW - Fetal growth

KW - Nonrenal regulation of blood pressure

KW - Placental water exchange

KW - Plasma renin activity

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Normal arterial blood pressure in the nephrectomized fetal lamb

Abstract

Keywords

ASJC Scopus subject areas

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