Ocular tuberculosis

Daniel M. Albert, Meisha L. Raven

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Maitre-Jan (1) is often credited with publishing the earliest description of ocular tuberculosis (1707). Major contributions to the understanding of the disease mechanism were not made until the latter part of the 19th century. In 1855, Eduard von Jaeger first described the ophthalmoscopic appearance of choroidal tubercles (2). Cohnheim, in 1867 (3), showed that choroidal tubercles were similar microscopically to tubercles found elsewhere in the body and postulated that ocular involvement was a metastatic manifestation of systemic infection. In addition, Cohnheim was able to produce similar lesions in guinea pigs by injecting them with tuberculous material. In 1882, Koch identified the tubercle bacillus as the causative agent (4), and 1 year later, Julius von Michel identified the organism in the eye (5).

Original languageEnglish (US)
Title of host publicationTuberculosis and Nontuberculous Mycobacterial Infections
Number of pages18
ISBN (Electronic)9781683670605
ISBN (Print)9781555819859
StatePublished - Jan 1 2017
Externally publishedYes


  • Choroidal tuberculomas
  • Choroiditis
  • Ciliary body tuberculoma
  • Clinical diagnosis
  • Ocular tuberculosis
  • Orbital tuberculosis
  • Systemic antituberculosis therapy
  • Tuberculous panophthalmitis
  • Tuberculous retinitis

ASJC Scopus subject areas

  • General Medicine
  • General Immunology and Microbiology


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