Office-based laryngeal maging in awake patients with swept-source optical coherence tomography

Lingfeng Yu, Gangjun Liu, Shuguang Guo, Brian J.F. Wong, Zhongping Chen

Research output: Contribution to journalConference articlepeer-review


Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the human larynx during surgical endoscopy. The design of a long GRIN lens based probe capable of capturing images of the human larynx by use of a swept-source OCT during a typical office-based laryngoscopy examination is presented. An optical-ballast-based 4F optical relay system is proposed to realize variable working distance with a constant optical delay. In vivo OCT imaging of the human larynx is demonstrated with 40 fame/second. Office-based OCT is a promising imaging modality to study the larynx.

Original languageEnglish (US)
Article number71682A
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
StatePublished - 2009
Externally publishedYes
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII - San Jose, CA, United States
Duration: Jan 26 2009Jan 28 2009


  • Biomedical imaging
  • Early diagnosis
  • Laryngeal cancer
  • Larynx
  • Optical coherence tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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