Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience

Angelena Crown; Elizabeth Carlson; Flavio G. Rocha; Janie W. Grumley

doi:10.1111/tbj.14093

Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience

Angelena Crown, Elizabeth Carlson, Flavio G. Rocha, Janie W. Grumley

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Intraoperative radiation therapy (IORT) has been shown to reduce local recurrence rates among women with early-stage invasive ductal carcinoma, but data regarding its use among women with in situ carcinoma are limited. In this single-institution study, 50 women with in situ carcinoma were treated with oncoplastic breast-conserving surgery (OPS) and single-dose IORT. All 50 patients had “no tumor on ink,” but 9 (16%) had margins < 2 mm and required additional therapy. No local recurrences were observed after a median follow-up of 46 months. Single-dose IORT is an efficacious treatment for well-selected patients with DCIS.

Original language	English (US)
Pages (from-to)	2391-2394
Number of pages	4
Journal	Breast Journal
Volume	26
Issue number	12
DOIs	https://doi.org/10.1111/tbj.14093
State	Published - Dec 2020
Externally published	Yes

Keywords

ductal Carcinoma in situ
early Stage Breast cancer
intraoperative radiation therapy

ASJC Scopus subject areas

Internal Medicine
Surgery
Oncology

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10.1111/tbj.14093

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title = "Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience",

abstract = "Intraoperative radiation therapy (IORT) has been shown to reduce local recurrence rates among women with early-stage invasive ductal carcinoma, but data regarding its use among women with in situ carcinoma are limited. In this single-institution study, 50 women with in situ carcinoma were treated with oncoplastic breast-conserving surgery (OPS) and single-dose IORT. All 50 patients had “no tumor on ink,” but 9 (16%) had margins < 2 mm and required additional therapy. No local recurrences were observed after a median follow-up of 46 months. Single-dose IORT is an efficacious treatment for well-selected patients with DCIS.",

keywords = "ductal Carcinoma in situ, early Stage Breast cancer, intraoperative radiation therapy",

author = "Angelena Crown and Elizabeth Carlson and Rocha, {Flavio G.} and Grumley, {Janie W.}",

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T1 - Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast

T2 - A single-center experience

AU - Crown, Angelena

AU - Carlson, Elizabeth

AU - Rocha, Flavio G.

AU - Grumley, Janie W.

PY - 2020/12

Y1 - 2020/12

N2 - Intraoperative radiation therapy (IORT) has been shown to reduce local recurrence rates among women with early-stage invasive ductal carcinoma, but data regarding its use among women with in situ carcinoma are limited. In this single-institution study, 50 women with in situ carcinoma were treated with oncoplastic breast-conserving surgery (OPS) and single-dose IORT. All 50 patients had “no tumor on ink,” but 9 (16%) had margins < 2 mm and required additional therapy. No local recurrences were observed after a median follow-up of 46 months. Single-dose IORT is an efficacious treatment for well-selected patients with DCIS.

AB - Intraoperative radiation therapy (IORT) has been shown to reduce local recurrence rates among women with early-stage invasive ductal carcinoma, but data regarding its use among women with in situ carcinoma are limited. In this single-institution study, 50 women with in situ carcinoma were treated with oncoplastic breast-conserving surgery (OPS) and single-dose IORT. All 50 patients had “no tumor on ink,” but 9 (16%) had margins < 2 mm and required additional therapy. No local recurrences were observed after a median follow-up of 46 months. Single-dose IORT is an efficacious treatment for well-selected patients with DCIS.

KW - ductal Carcinoma in situ

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KW - intraoperative radiation therapy

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Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience

Abstract

Keywords

ASJC Scopus subject areas

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