Operative Mortality Rates of Acoustic Neuroma Surgery: A National Cancer Database Analysis

Shearwood McClelland, Ellen Kim, James D. Murphy, Jerry J. Jaboin

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Introduction: Optimal acoustic neuroma (AN) management involves choosing between three treatment modalities: microsurgical excision, radiation, or observation with serial imaging. The reported in-hospital mortality rate of surgery for AN in the United States is 0.5%. However, there has yet to be a nationwide examination of the AN surgery mortality rate encompassing the period beyond initial hospital discharge. Methods: The National Cancer Data Base (NCDB) from 2004 to 2013 identified AN patients receiving surgery. Multivariate logistic regression assessed 30-day operative mortality, adjusting for several variables including patient age, race, sex, income, geographic region, primary payer for care, tumor size, and medical comorbidities. Results: Ten thousand one hundred thirty six patients received surgery as solitary treatment for AN. Mortality at 30 days postoperatively occurred in 49 patients (0.5%); only a Charlson/Deyo score of 2 (odds ratio [OR] = 6.6;95% confidence interval [CI] = 2.6-16.6; p = 0.002) was predictive of increased mortality. No other patient demographic including African-American race, minimum age of 65 or government insurance was predictive of 30-day operative mortality. Conclusions: The 30-day mortality rate following surgery for AN is 1 of 200 (0.5%), equivalent to the established in-hospital operative mortality rate, and 2.5 times higher than the cumulative assessment from single-center studies. No patient demographic other than increasing medical comorbidities reached significance in predicting 30-day operative mortality. The nearly identical rates of 30-day and in-hospital mortality from separate nationwide analyses indicate that nearly all of the operative mortality occurs before initial postoperative discharge from the hospital. This mortality rate provides a framework for comparing the true risks and benefits of surgery versus radiation or observation for AN.

Original languageEnglish (US)
Pages (from-to)751-753
Number of pages3
JournalOtology and Neurotology
Issue number5
StatePublished - Jun 1 2017


  • Acoustic neuroma
  • Mortality
  • National cancer data base
  • Surgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Sensory Systems
  • Otorhinolaryngology


Dive into the research topics of 'Operative Mortality Rates of Acoustic Neuroma Surgery: A National Cancer Database Analysis'. Together they form a unique fingerprint.

Cite this