Oral and oropharyngeal prevalence of Enterobacteriaceae in humans: a review

Christine M. Sedgley, Lakshman P. Samaranayake

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


Members of the Enterobacteriaceae family are widely distributed in nature and exhibit substantial diversity in ecology, host range and pathogenic potential for man. While wide discrepancies in methodology exist between epidemiological studies, the available data indicate an increased prevalence of oral and/or oropharyngeal Enterobacteriaceae carriage in patients with illnesses of varying severity compared with healthy subjects. This paper reviews the prevalence of Enterobacteriaceae in the oral and oropharyngeal region of healthy human subjects and those affected by different disease entities, and discusses the complexities associated with collating and interpreting such data. The effect of antimicrobials and antiseptics on oral and oropharyngeal Enterobacteriaceae has also been reviewed, while highlighting the gaps in knowledge and future research directions.

Original languageEnglish (US)
Pages (from-to)104-413
Number of pages310
JournalJournal of Oral Pathology & Medicine
Issue number3
StatePublished - Mar 1994
Externally publishedYes


  • Enterobacteriaceae
  • humans
  • oral
  • oropharyngeal
  • prevalence
  • review

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Oral Surgery
  • Otorhinolaryngology
  • Cancer Research
  • Periodontics


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