Orthobiologics in orthopedic applications: a report from the TMI Havemeyer meeting on orthobiologics

Christian Lattermann, Chilan B.G. Leite, David D. Frisbie, Theodore S. Schlegel, Larry R. Bramlage, Thomas Koch, Christopher Centeno, Laurie R. Goodrich, Brian Johnstone, Rocci Trumper, Ashlee Watts, Christopher Little, Frank Barry, Farsh Guilak, C. Wayne McIlwraith

Research output: Contribution to journalArticlepeer-review

Abstract

Readily available and effective therapeutic approaches are increasingly required to overcome the growing demand for optimized management of musculoskeletal degenerative conditions. The use of biologic therapies has been gaining ground in the orthopedic field by showing promising results. In order to review the current status of orthobiologics and to discuss the potential risks, benefits, and challenges of their implementation, a recent expert conference hosted by the C. Wayne McIlwraith Translational Medicine Institute (TMI), and funded by the Dorothy Havemeyer Foundation was held at Colorado State University, in conjunction with the official Opening of the TMI. This review summarizes the conference findings highlighting the scientific challenges, safety concerns, and translation of orthobiologics to clinical practice.

Original languageEnglish (US)
Article number100055
JournalJournal of Cartilage and Joint Preservation
Volume2
Issue number3
DOIs
StatePublished - Sep 2022

Keywords

  • Orthobiologics
  • Platelet-rich plasma
  • Regenerative medicine
  • Stem cell therapy

ASJC Scopus subject areas

  • Surgery
  • Immunology and Allergy
  • Rheumatology
  • Orthopedics and Sports Medicine
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)

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