Pairing food and drink: A physiological model of blood ethanol levels for a variety of drinking behaviors

Sharon Moore; Ami Radunskaya; Elizabeth Zollinger; Kathleen A. Grant; Steven Gonzales; Nicole A.R. Walter; Erich J. Baker

doi:10.1016/j.mbs.2022.108778

Pairing food and drink: A physiological model of blood ethanol levels for a variety of drinking behaviors

Sharon Moore, Ami Radunskaya, Elizabeth Zollinger, Kathleen A. Grant, Steven Gonzales, Nicole A.R. Walter, Erich J. Baker

Oregon National Primate Research Center

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We present a blood ethanol concentration compartment model which utilizes an animal's ethanol intake, food intake, and weight to predict the animal's blood ethanol concentration at any given time. By incorporating the food digestion process into the model we can predict blood ethanol concentration levels over time for a variety of drinking and eating scenarios. The model is calibrated and validated using data from cohorts of male monkeys, and is able to capture blood ethanol concentration kinetics of the monkeys from a variety of drinking behavior classifications.

Original language	English (US)
Article number	108778
Journal	Mathematical Biosciences
Volume	345
DOIs	https://doi.org/10.1016/j.mbs.2022.108778
State	Published - Mar 2022

Keywords

Alcohol use disorder
Differential equations
Drinking classification
Mathematical modeling

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Agricultural and Biological Sciences
Applied Mathematics

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title = "Pairing food and drink: A physiological model of blood ethanol levels for a variety of drinking behaviors",

abstract = "We present a blood ethanol concentration compartment model which utilizes an animal's ethanol intake, food intake, and weight to predict the animal's blood ethanol concentration at any given time. By incorporating the food digestion process into the model we can predict blood ethanol concentration levels over time for a variety of drinking and eating scenarios. The model is calibrated and validated using data from cohorts of male monkeys, and is able to capture blood ethanol concentration kinetics of the monkeys from a variety of drinking behavior classifications.",

keywords = "Alcohol use disorder, Differential equations, Drinking classification, Mathematical modeling",

author = "Sharon Moore and Ami Radunskaya and Elizabeth Zollinger and Grant, {Kathleen A.} and Steven Gonzales and Walter, {Nicole A.R.} and Baker, {Erich J.}",

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doi = "10.1016/j.mbs.2022.108778",

language = "English (US)",

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T2 - A physiological model of blood ethanol levels for a variety of drinking behaviors

AU - Moore, Sharon

AU - Radunskaya, Ami

AU - Zollinger, Elizabeth

AU - Grant, Kathleen A.

AU - Gonzales, Steven

AU - Walter, Nicole A.R.

AU - Baker, Erich J.

PY - 2022/3

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AB - We present a blood ethanol concentration compartment model which utilizes an animal's ethanol intake, food intake, and weight to predict the animal's blood ethanol concentration at any given time. By incorporating the food digestion process into the model we can predict blood ethanol concentration levels over time for a variety of drinking and eating scenarios. The model is calibrated and validated using data from cohorts of male monkeys, and is able to capture blood ethanol concentration kinetics of the monkeys from a variety of drinking behavior classifications.

KW - Alcohol use disorder

KW - Differential equations

KW - Drinking classification

KW - Mathematical modeling

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JO - Mathematical Biosciences

JF - Mathematical Biosciences

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Pairing food and drink: A physiological model of blood ethanol levels for a variety of drinking behaviors

Abstract

Keywords

ASJC Scopus subject areas

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