Parkinson's disease and solvents: Is there a causal link?

J. Reis; E. Benbrick; V. Bonneterre; P. S. Spencer

doi:10.1016/j.neurol.2016.09.012

Parkinson's disease and solvents: Is there a causal link?

J. Reis, E. Benbrick, V. Bonneterre, P. S. Spencer

Neurology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We report here on chronic neurological impairment in three car painters with constant occupational exposure to organic solvents. All had a clinical presentation of Parkinson's disease and, in all cases, SPECT DaTscan brain imaging, using ¹²³I-FP-CIT, showed bilateral reduction of tracer uptake in the basal ganglia, evidence of dysfunction at the dopaminergic terminal.

Original language	English (US)
Pages (from-to)	761-765
Number of pages	5
Journal	Revue Neurologique
Volume	172
Issue number	12
DOIs	https://doi.org/10.1016/j.neurol.2016.09.012
State	Published - Dec 1 2016

Keywords

DaTscan
Organic solvents
Painters
Parkinson's disease

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1016/j.neurol.2016.09.012

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title = "Parkinson's disease and solvents: Is there a causal link?",

abstract = "We report here on chronic neurological impairment in three car painters with constant occupational exposure to organic solvents. All had a clinical presentation of Parkinson's disease and, in all cases, SPECT DaTscan brain imaging, using 123I-FP-CIT, showed bilateral reduction of tracer uptake in the basal ganglia, evidence of dysfunction at the dopaminergic terminal.",

keywords = "DaTscan, Organic solvents, Painters, Parkinson's disease",

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AU - Bonneterre, V.

AU - Spencer, P. S.

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AB - We report here on chronic neurological impairment in three car painters with constant occupational exposure to organic solvents. All had a clinical presentation of Parkinson's disease and, in all cases, SPECT DaTscan brain imaging, using 123I-FP-CIT, showed bilateral reduction of tracer uptake in the basal ganglia, evidence of dysfunction at the dopaminergic terminal.

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KW - Painters

KW - Parkinson's disease

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Parkinson's disease and solvents: Is there a causal link?

Abstract

Keywords

ASJC Scopus subject areas

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