Paroxysmal nocturnal hemoglobinuria presenting with a left intraventricular thrombus in a patient with prior thymoma and aplastic anemia

Yazan Migdady; Adam J. Olszewski

doi:10.4137/CMO.S8442

Paroxysmal nocturnal hemoglobinuria presenting with a left intraventricular thrombus in a patient with prior thymoma and aplastic anemia

Yazan Migdady, Adam J. Olszewski

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplas-tic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed.

Original language	English (US)
Pages (from-to)	343-348
Number of pages	6
Journal	Clinical Medicine Insights: Oncology
Volume	5
DOIs	https://doi.org/10.4137/CMO.S8442
State	Published - 2011
Externally published	Yes

Keywords

Aplastic anemia
Cardiac thrombosis
Paroxysmal nocturnal hemoglobinuria
Thymoma

ASJC Scopus subject areas

Oncology

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10.4137/CMO.S8442

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abstract = "We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplas-tic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed.",

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N2 - We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplas-tic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed.

AB - We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplas-tic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed.

KW - Aplastic anemia

KW - Cardiac thrombosis

KW - Paroxysmal nocturnal hemoglobinuria

KW - Thymoma

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ER -

Paroxysmal nocturnal hemoglobinuria presenting with a left intraventricular thrombus in a patient with prior thymoma and aplastic anemia

Abstract

Keywords

ASJC Scopus subject areas

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