TY - JOUR
T1 - Participatory Research to Advance Colon Cancer Prevention (PROMPT)
T2 - Study protocol for a pragmatic trial
AU - Thompson, Jamie H.
AU - Davis, Melinda M.
AU - Leo, Michael C.
AU - Schneider, Jennifer L.
AU - Smith, David H.
AU - Petrik, Amanda F.
AU - Castillo, Melissa
AU - Younger, Brittany
AU - Coronado, Gloria D.
N1 - Funding Information:
Research reported in this publication was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health under Award Number U01MD010665 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Publisher Copyright:
© 2018
PY - 2018/4
Y1 - 2018/4
N2 - Background: Colon cancer is the second leading cause of cancer deaths in the United States. The Participatory Research to Advance Colon Cancer Prevention (PROMPT) study is a collaboration between two research institutions and a federally qualified health center (FQHC). The study seeks to raise colon cancer screening rates using a direct-mail fecal immunochemical testing (FIT) and reminder program in an FQHC serving a predominantly Latino population in California. Methods: PROMPT is a pragmatic trial enrolling 16 clinics. The study will test automated and live prompts (i.e., alerts, reminders) to a direct-mail FIT program in two phases. In Phase I, we tailored and defined intervention components for the pilot using a community-based participatory research approach called boot camp translation. We then plan to conduct a three-arm patient-randomized comparative effectiveness trial in two pilot clinics to compare 1) automated prompts, 2) live prompts, and 3) a combination of automated plus live prompts to alert and remind patients to complete screening. In Phase II, the adapted best practice intervention will be spread to additional clinics within the FQHC (estimated population 27,000) and assessed for effectiveness. Patient and staff interviews will be conducted to explore receptivity to the program and identify barriers to implementation. Discussion: This pragmatic trial applies innovative approaches to engage diverse stakeholders and will test the effectiveness and spread of a direct-mail plus reminder program. If successful, the program will provide a model for a cost-effective method to raise colon cancer screening rates among Latino patients receiving care in FQHCs. Trial registration: National Clinical Trial (NCT) Identifier NCT03167125.
AB - Background: Colon cancer is the second leading cause of cancer deaths in the United States. The Participatory Research to Advance Colon Cancer Prevention (PROMPT) study is a collaboration between two research institutions and a federally qualified health center (FQHC). The study seeks to raise colon cancer screening rates using a direct-mail fecal immunochemical testing (FIT) and reminder program in an FQHC serving a predominantly Latino population in California. Methods: PROMPT is a pragmatic trial enrolling 16 clinics. The study will test automated and live prompts (i.e., alerts, reminders) to a direct-mail FIT program in two phases. In Phase I, we tailored and defined intervention components for the pilot using a community-based participatory research approach called boot camp translation. We then plan to conduct a three-arm patient-randomized comparative effectiveness trial in two pilot clinics to compare 1) automated prompts, 2) live prompts, and 3) a combination of automated plus live prompts to alert and remind patients to complete screening. In Phase II, the adapted best practice intervention will be spread to additional clinics within the FQHC (estimated population 27,000) and assessed for effectiveness. Patient and staff interviews will be conducted to explore receptivity to the program and identify barriers to implementation. Discussion: This pragmatic trial applies innovative approaches to engage diverse stakeholders and will test the effectiveness and spread of a direct-mail plus reminder program. If successful, the program will provide a model for a cost-effective method to raise colon cancer screening rates among Latino patients receiving care in FQHCs. Trial registration: National Clinical Trial (NCT) Identifier NCT03167125.
KW - Boot camp translation
KW - Colon cancer screening
KW - Community-based participatory research
KW - Fecal immunochemical test
KW - Pragmatic study
UR - http://www.scopus.com/inward/record.url?scp=85041505669&partnerID=8YFLogxK
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U2 - 10.1016/j.cct.2018.02.001
DO - 10.1016/j.cct.2018.02.001
M3 - Article
C2 - 29408304
AN - SCOPUS:85041505669
SN - 1551-7144
VL - 67
SP - 11
EP - 15
JO - Contemporary Clinical Trials
JF - Contemporary Clinical Trials
ER -