Percutaneous transjugular kidney biopsy in swine with use of a side- cutting needle with a blunt-tipped stylet

Paul C. Lakin, Dusan Pavcnik, Robert D. Bloch, Barry T. Uchida, Christopher L. Corless, Hans A. Timmermans, Yasushi Kubota

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


PURPOSE: To evaluate a new 19-gauge blunt-tipped, side-cutting, single throw transjugular biopsy needle for transvenous kidney biopsies. MATERIALS AND METHODS: Transjugular transvenous kidney biopsies were performed with a modified 70-cm biopsy needle utilizing fluoroscopic guidance in nine swine. Three tissue specimens were obtained with four biopsy device passes in five animals and three biopsy device passes in four animals. Renal arteriography and venography were performed immediately before and after renal biopsy. Five animals were killed immediately after biopsy. Four animals were allowed to recover and underwent arteriography and venography prior to being killed, which varied from 1 to 6 weeks. Gross and histologic examinations of the biopsied kidney were performed after euthanasia. A pathologist reviewed all biopsy specimens for quality based on the number of glomeruli present. RESULTS: Results of immediate and delayed arteriography and venography were normal in all cases. Histologic evaluation of all biopsy specimens demonstrated a range of two to 13 glomeruli per sample (mean, 6.5), with successful acquisition of the cortex. In one animal killed immediately after biopsy, a small subcapsular hematoma was present. CONCLUSION: The 19-gauge, side-cut biopsy needle with a blunt-tip stylet proved to be efficacious for obtaining renal cortical samples in right swine kidneys via a transjugular approach.

Original languageEnglish (US)
Pages (from-to)1229-1232
Number of pages4
JournalJournal of Vascular and Interventional Radiology
Issue number9
StatePublished - Oct 1999


  • Biopsies, technology
  • Kidney, biopsy
  • Kidney, interventional procedures

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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