Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders

Dylan Haynes; Taylor Reiter; Rose Velasco; Matthew Chang; Rajan Kulkarni; Gail Kent; Jennifer Strunck; Pamela Cassidy; Teri M. Greiling

doi:10.1016/j.jid.2022.09.005

Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders

Dylan Haynes, Taylor Reiter, Rose Velasco, Matthew Chang, Rajan Kulkarni, Gail Kent, Jennifer Strunck, Pamela Cassidy, Teri M. Greiling

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	501-504.e1
Journal	Journal of Investigative Dermatology
Volume	143
Issue number	3
DOIs	https://doi.org/10.1016/j.jid.2022.09.005
State	Published - Mar 2023

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

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10.1016/j.jid.2022.09.005

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Haynes, D., Reiter, T., Velasco, R., Chang, M., Kulkarni, R., Kent, G., Strunck, J., Cassidy, P., & Greiling, T. M. (2023). Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders. Journal of Investigative Dermatology, 143(3), 501-504.e1. https://doi.org/10.1016/j.jid.2022.09.005

Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders. / Haynes, Dylan; Reiter, Taylor; Velasco, Rose et al.
In: Journal of Investigative Dermatology, Vol. 143, No. 3, 03.2023, p. 501-504.e1.

Research output: Contribution to journal › Article › peer-review

Haynes, D, Reiter, T, Velasco, R, Chang, M , Kulkarni, R, Kent, G, Strunck, J, Cassidy, P & Greiling, TM 2023, 'Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders', Journal of Investigative Dermatology, vol. 143, no. 3, pp. 501-504.e1. https://doi.org/10.1016/j.jid.2022.09.005

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title = "Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders",

author = "Dylan Haynes and Taylor Reiter and Rose Velasco and Matthew Chang and Rajan Kulkarni and Gail Kent and Jennifer Strunck and Pamela Cassidy and Greiling, {Teri M.}",

note = "Funding Information: This study was funded by an investigator-initiated grant from Eli Lilly and Company. The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and decision to submit the manuscript for publication. Data storage through REDCap was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under award No. UL1TR0002369. Funding Information: TMG has received research funding to study pityriasis rubra pilaris from Eli Lilly and Co for this study; has funding from Janssen Scientific Affairs to study unrelatd aspects of pityriasis rubra pilaris; and is an author for UpToDate on pityriasis rubra pilaris. The remaining authors state no conflict of interest. ",

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AU - Haynes, Dylan

AU - Reiter, Taylor

AU - Velasco, Rose

AU - Chang, Matthew

AU - Kulkarni, Rajan

AU - Kent, Gail

AU - Strunck, Jennifer

AU - Cassidy, Pamela

AU - Greiling, Teri M.

N1 - Funding Information: This study was funded by an investigator-initiated grant from Eli Lilly and Company. The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and decision to submit the manuscript for publication. Data storage through REDCap was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under award No. UL1TR0002369. Funding Information: TMG has received research funding to study pityriasis rubra pilaris from Eli Lilly and Co for this study; has funding from Janssen Scientific Affairs to study unrelatd aspects of pityriasis rubra pilaris; and is an author for UpToDate on pityriasis rubra pilaris. The remaining authors state no conflict of interest.

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Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders

ASJC Scopus subject areas

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