Abstract
Polarized light imaging can facilitate clinical mapping of skin cancer margins and can potentially guide clinical excision. A real-time hand-held polarized-light system was built to image skin lesions in the clinic. The system consisted of two 8-bit CCD cameras (Camera 1 and Camera 2) mounted on two sides of a polarizing beamsplitter. A polarized light source was mounted on the camera assembly and illuminated the patient's skin. Light was polarized parallel to the source-patient-camera plane. The light, reflected from the patient, was collected with an objective lens mounted on the beam splitter and divided into a horizontal (H) and vertical (V) component. The H component was collected by Camera 1, and the V component was collected by Camera 2. A new image was generated based on the polarization ratio (H - V)/(H + V) and displayed. This image was sensitive to the superficial skin layer and some early clinical examples are presented. A web version of this paper is available at the following web site: optics.s.gu.ru/SFM/2002/internet/Jessica/.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 284-293 |
| Number of pages | 10 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 5068 |
| State | Published - 2002 |
| Externally published | Yes |
| Event | Saratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV - Saratov, Russian Federation Duration: Oct 1 2002 → Oct 4 2002 |
Keywords
- Imaging
- Melanoma
- Polarization
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering