Polymeric PARACEST agents for enhancing MRI contrast sensitivity

Yunkou Wu, Youfu Zhou, Olivier Ouari, Mark Woods, Piyu Zhao, Todd C. Soesbe, Garry E. Kiefer, A. Dean Sherry

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


Linear polymers of PARACEST agents were prepared by using classical free radical chain polymerization conditions. The Eu3+-polymers exhibited similar intermediate-to-slow water exchange and CEST characteristics as the Eu3+-monomers. This provided an avenue to lower the detection limit of these imaging agents substantially and makes them potentially useful as MRI sensors for molecular imaging.

Original languageEnglish (US)
Pages (from-to)13854-13855
Number of pages2
JournalJournal of the American Chemical Society
Issue number42
StatePublished - Oct 22 2008
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


Dive into the research topics of 'Polymeric PARACEST agents for enhancing MRI contrast sensitivity'. Together they form a unique fingerprint.

Cite this