Possible adverse effects of drugs used in refractive surgery

Frederick W. Fraunfelder, Larry F. Rich

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Adverse drug reaction reports were compiled from the National Registry of Drug-Induced Ocular Side Effects, Casey Eye Institute, Portland, Oregon, USA; the United States Food and Drug Administration, Rockville, Maryland; the World Health Organization, Uppsala, Sweden; and a Medline literature review of the past 50 years. The reported side effects of mydriatics, cycloplegics, benzodiazepines, tetracyclines, iodine, topical anesthetics, medications used for hemostasis, non-steroidal antiinflammatory drugs, steroids, antibiotics, and artificial tears are described. Physicians should be aware of the side-effect profile and current industry standards for medications used in corneal refractive surgery, including off-label uses. Guidelines are provided for some classes of medications.

Original languageEnglish (US)
Pages (from-to)170-175
Number of pages6
JournalJournal of cataract and refractive surgery
Issue number1
StatePublished - Jan 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems


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