Promise and pitfalls of heavy-particles therapy

Timur Mitin, Anthony L. Zietman

Research output: Contribution to journalReview articlepeer-review

104 Scopus citations


Proton beam therapy, the most common form of heavy-particle radiation therapy, is not a new invention, but it has gained considerable public attention because of the high cost of installing and operating the rapidly increasing number of treatment centers. This article reviews the physical properties of proton beam therapy and focuses on the up-to-date clinical evidence comparing proton beam therapy with the more standard and widely available radiation therapy treatment alternatives. In a cost-conscious era of health care, the hypothetical benefits of proton beam therapy will have to be supported by demonstrable clinical gains. Proton beam therapy represents, through its scale and its cost, a battleground for the policy debate around managing expensive technology in modern medicine.

Original languageEnglish (US)
Pages (from-to)2855-2863
Number of pages9
JournalJournal of Clinical Oncology
Issue number26
StatePublished - Sep 10 2014

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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