TY - JOUR
T1 - Proton and Sodium 23 Magnetic Resonance Imaging of Human Ocular Tissues
T2 - A Model Study
AU - Kolodny, Nancy H.
AU - Gragoudas, Evangelos S.
AU - D'amico, Donald J.
AU - Kohler, Susan J.
AU - Seddon, Johanna M.
AU - Murphy, Elizabeth J.
AU - Yun, Christina
AU - Albert, Daniel M.
PY - 1987/11
Y1 - 1987/11
N2 - Clinical evaluation of uveal melanomas by magnetic resonance imaging (MRI) techniques depends on developing an understanding of the appearance of these tumors in magnetic resonance (MR) images. We have determined MR characteristics of uveal melanomas by proton (1H) and sodium 23 MRI of freshly enucleated human eyes at 1.5 tesla. The MR images were obtained using two-turn proton and 23Na surface coils, designed to both transmit and receive the radiofrequency signal. Proton MRI techniques included saturation recovery and spin echo; the gradient-recalled echo technique was used for 23Na MRI. Proton and 23Na MR images provide complementary information; contrast between intraocular tumors and vitreous, lens, or subretinal hemorrhage may be varied by using MR pulse sequences that emphasize tissues based on T1, T2, proton, or sodium density values. A combination of proton and 23Na MRI provides differentiation between normal ocular structures and intraocular tumors, as well as associated complications, such as retinal detachments and subretinal hemorrhages.
AB - Clinical evaluation of uveal melanomas by magnetic resonance imaging (MRI) techniques depends on developing an understanding of the appearance of these tumors in magnetic resonance (MR) images. We have determined MR characteristics of uveal melanomas by proton (1H) and sodium 23 MRI of freshly enucleated human eyes at 1.5 tesla. The MR images were obtained using two-turn proton and 23Na surface coils, designed to both transmit and receive the radiofrequency signal. Proton MRI techniques included saturation recovery and spin echo; the gradient-recalled echo technique was used for 23Na MRI. Proton and 23Na MR images provide complementary information; contrast between intraocular tumors and vitreous, lens, or subretinal hemorrhage may be varied by using MR pulse sequences that emphasize tissues based on T1, T2, proton, or sodium density values. A combination of proton and 23Na MRI provides differentiation between normal ocular structures and intraocular tumors, as well as associated complications, such as retinal detachments and subretinal hemorrhages.
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U2 - 10.1001/archopht.1987.01060110078036
DO - 10.1001/archopht.1987.01060110078036
M3 - Article
C2 - 2823760
AN - SCOPUS:0023239810
SN - 0003-9950
VL - 105
SP - 1532
EP - 1536
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 11
ER -