Psychopharmacology of borderline personality disorder

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13 Scopus citations


Psychopharmacology is widely used in the treatment of borderline personality disorder. However, support for this form of treatment has been largely based on case reports, case series, and open-label clinical trials. This evidence-based review examines the most recent randomized controlled trials of psychopharmacology in the treatment of borderline personality disorder, with a goal of highlighting the most promising pharmacotherapy for use in current clinical practice, as well as for future large-scale research testing. The results and limitations of the randomized controlled trial data are presented along with case vignettes illustrating the complexity of the disorder and the heterogeneity of its treatment. To date, there is at least some evidence-based support for the use of antipsychotics (conventional and atypical), monoamine oxidase inhibitors, serotonin reuptake inhibitors, and omega-3 fatty acids in the treatment of borderline personality disorders.

Original languageEnglish (US)
Pages (from-to)225-231
Number of pages7
JournalCurrent Psychiatry Reports
Issue number3
StatePublished - Jun 2004
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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