Pulmonary fibrosis from amorphous silica dust, a product of silica vapor

Vitolds C. Vitums, Miles J. Edwards, Nelson R. Niles

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


After prolonged occupational exposure to amorphous silica dust-a product of vaporized crystalline silica (quartz)-eleven out of forty workers showed reticular and/or nodular abnormalities in roentgenograms of the chest. From this group, we present three illustrative cases. These had widespread pulmonary disease with granulomatous nodules and fibrosis (documelltd histologically in two cases), but there was 110 demonstrable restrictive impairment of pulmollary function. We discuss the possible imponance of this previollsly underestimated toxicity, especially in all industrial setting.

Original languageEnglish (US)
Pages (from-to)62-68
Number of pages7
JournalArchives of Environmental Health
Issue number2
StatePublished - Mar 1977
Externally publishedYes

ASJC Scopus subject areas

  • Environmental Chemistry
  • Environmental Science(all)
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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