Pupillary dilations in a Target/Distractor visual task paradigm and attention deficit hyperactivity disorder (ADHD)

Claudio M. Privitera; Sean Noah; Thom Carney; Stanley A. Klein; Agatha Lenartowicz; Stephen P. Hinshaw; James T. McCracken; Joel T. Nigg; Sarah L. Karalunas; Rory C. Reid; Mercedes T. Oliva; Samantha S. Betts; Gregory V. Simpson

doi:10.1016/j.neulet.2023.137556

Pupillary dilations in a Target/Distractor visual task paradigm and attention deficit hyperactivity disorder (ADHD)

Claudio M. Privitera, Sean Noah, Thom Carney, Stanley A. Klein, Agatha Lenartowicz, Stephen P. Hinshaw, James T. McCracken, Joel T. Nigg, Sarah L. Karalunas, Rory C. Reid, Mercedes T. Oliva, Samantha S. Betts, Gregory V. Simpson

Research output: Contribution to journal › Article › peer-review

Abstract

ADHD is a neurocognitive disorder characterized by attention difficulties, hyperactivity, and impulsivity, often persisting into adulthood with substantial personal and societal consequences. Despite the importance of neurophysiological assessment and treatment monitoring tests, their availability outside of research settings remains limited. Cognitive neuroscience investigations have identified distinct components associated with ADHD, including deficits in sustained attention, inefficient enhancement of attended Targets, and altered suppression of ignored Distractors. In this study, we examined pupil activity in control and ADHD subjects during a sustained visual attention task specifically designed to evaluate the mechanisms underlying Target enhancement and Distractor suppression. Our findings revealed some distinguishing factors between the two groups which we discuss in light of their neurobiological implications.

Original language	English (US)
Article number	137556
Journal	Neuroscience Letters
Volume	818
DOIs	https://doi.org/10.1016/j.neulet.2023.137556
State	Published - Jan 1 2024

ASJC Scopus subject areas

General Neuroscience

Access to Document

10.1016/j.neulet.2023.137556

Cite this

Privitera, C. M., Noah, S., Carney, T., Klein, S. A., Lenartowicz, A., Hinshaw, S. P., McCracken, J. T., Nigg, J. T., Karalunas, S. L., Reid, R. C., Oliva, M. T., Betts, S. S., & Simpson, G. V. (2024). Pupillary dilations in a Target/Distractor visual task paradigm and attention deficit hyperactivity disorder (ADHD). Neuroscience Letters, 818, Article 137556. https://doi.org/10.1016/j.neulet.2023.137556

@article{3c950b73dfa54ca48978957f6c656124,

title = "Pupillary dilations in a Target/Distractor visual task paradigm and attention deficit hyperactivity disorder (ADHD)",

abstract = "ADHD is a neurocognitive disorder characterized by attention difficulties, hyperactivity, and impulsivity, often persisting into adulthood with substantial personal and societal consequences. Despite the importance of neurophysiological assessment and treatment monitoring tests, their availability outside of research settings remains limited. Cognitive neuroscience investigations have identified distinct components associated with ADHD, including deficits in sustained attention, inefficient enhancement of attended Targets, and altered suppression of ignored Distractors. In this study, we examined pupil activity in control and ADHD subjects during a sustained visual attention task specifically designed to evaluate the mechanisms underlying Target enhancement and Distractor suppression. Our findings revealed some distinguishing factors between the two groups which we discuss in light of their neurobiological implications.",

author = "Privitera, {Claudio M.} and Sean Noah and Thom Carney and Klein, {Stanley A.} and Agatha Lenartowicz and Hinshaw, {Stephen P.} and McCracken, {James T.} and Nigg, {Joel T.} and Karalunas, {Sarah L.} and Reid, {Rory C.} and Oliva, {Mercedes T.} and Betts, {Samantha S.} and Simpson, {Gregory V.}",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2024",

month = jan,

day = "1",

doi = "10.1016/j.neulet.2023.137556",

language = "English (US)",

volume = "818",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Pupillary dilations in a Target/Distractor visual task paradigm and attention deficit hyperactivity disorder (ADHD)

AU - Privitera, Claudio M.

AU - Noah, Sean

AU - Carney, Thom

AU - Klein, Stanley A.

AU - Lenartowicz, Agatha

AU - Hinshaw, Stephen P.

AU - McCracken, James T.

AU - Nigg, Joel T.

AU - Karalunas, Sarah L.

AU - Reid, Rory C.

AU - Oliva, Mercedes T.

AU - Betts, Samantha S.

AU - Simpson, Gregory V.

PY - 2024/1/1

Y1 - 2024/1/1

N2 - ADHD is a neurocognitive disorder characterized by attention difficulties, hyperactivity, and impulsivity, often persisting into adulthood with substantial personal and societal consequences. Despite the importance of neurophysiological assessment and treatment monitoring tests, their availability outside of research settings remains limited. Cognitive neuroscience investigations have identified distinct components associated with ADHD, including deficits in sustained attention, inefficient enhancement of attended Targets, and altered suppression of ignored Distractors. In this study, we examined pupil activity in control and ADHD subjects during a sustained visual attention task specifically designed to evaluate the mechanisms underlying Target enhancement and Distractor suppression. Our findings revealed some distinguishing factors between the two groups which we discuss in light of their neurobiological implications.

AB - ADHD is a neurocognitive disorder characterized by attention difficulties, hyperactivity, and impulsivity, often persisting into adulthood with substantial personal and societal consequences. Despite the importance of neurophysiological assessment and treatment monitoring tests, their availability outside of research settings remains limited. Cognitive neuroscience investigations have identified distinct components associated with ADHD, including deficits in sustained attention, inefficient enhancement of attended Targets, and altered suppression of ignored Distractors. In this study, we examined pupil activity in control and ADHD subjects during a sustained visual attention task specifically designed to evaluate the mechanisms underlying Target enhancement and Distractor suppression. Our findings revealed some distinguishing factors between the two groups which we discuss in light of their neurobiological implications.

UR - http://www.scopus.com/inward/record.url?scp=85177183132&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85177183132&partnerID=8YFLogxK

U2 - 10.1016/j.neulet.2023.137556

DO - 10.1016/j.neulet.2023.137556

M3 - Article

C2 - 37951300

AN - SCOPUS:85177183132

SN - 0304-3940

VL - 818

JO - Neuroscience Letters

JF - Neuroscience Letters

M1 - 137556

ER -

Pupillary dilations in a Target/Distractor visual task paradigm and attention deficit hyperactivity disorder (ADHD)

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this