Renin-Secreting Ovarian Adult Granulosa Cell Tumor in a Patient With New-Onset Hypertension and Hypokalemia

Rowan Karaman; Jin Xu; Ross F. Harrison; David M. Kushner; Paul S. Weisman; Yoram Shenker

doi:10.4158/ACCR-2018-0355

Renin-Secreting Ovarian Adult Granulosa Cell Tumor in a Patient With New-Onset Hypertension and Hypokalemia

Rowan Karaman, Jin Xu, Ross F. Harrison, David M. Kushner, Paul S. Weisman, Yoram Shenker

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objective: To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia. Methods: We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor. Results: A 31-year-old female presented with hypertension and amenorrhea. She was found to have spontaneous hypokalemia. Computed tomography scan showed a pelvic mass which was resected and found to be a renin-secreting ovarian adult granulosa cell tumor. The hypertension and hypokalemia resolved after the mass was resected. Conclusion: Renin-secreting ovarian adult granulosa cell tumors are rare causes of hyperreninemia leading to hypertension and hypokalemia.

Original language	English (US)
Pages (from-to)	e168-e171
Journal	AACE Clinical Case Reports
Volume	5
Issue number	2
DOIs	https://doi.org/10.4158/ACCR-2018-0355
State	Published - Mar 1 2019
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism

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10.4158/ACCR-2018-0355

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title = "Renin-Secreting Ovarian Adult Granulosa Cell Tumor in a Patient With New-Onset Hypertension and Hypokalemia",

abstract = "Objective: To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia. Methods: We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor. Results: A 31-year-old female presented with hypertension and amenorrhea. She was found to have spontaneous hypokalemia. Computed tomography scan showed a pelvic mass which was resected and found to be a renin-secreting ovarian adult granulosa cell tumor. The hypertension and hypokalemia resolved after the mass was resected. Conclusion: Renin-secreting ovarian adult granulosa cell tumors are rare causes of hyperreninemia leading to hypertension and hypokalemia.",

author = "Rowan Karaman and Jin Xu and Harrison, {Ross F.} and Kushner, {David M.} and Weisman, {Paul S.} and Yoram Shenker",

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T1 - Renin-Secreting Ovarian Adult Granulosa Cell Tumor in a Patient With New-Onset Hypertension and Hypokalemia

AU - Karaman, Rowan

AU - Xu, Jin

AU - Harrison, Ross F.

AU - Kushner, David M.

AU - Weisman, Paul S.

AU - Shenker, Yoram

PY - 2019/3/1

Y1 - 2019/3/1

N2 - Objective: To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia. Methods: We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor. Results: A 31-year-old female presented with hypertension and amenorrhea. She was found to have spontaneous hypokalemia. Computed tomography scan showed a pelvic mass which was resected and found to be a renin-secreting ovarian adult granulosa cell tumor. The hypertension and hypokalemia resolved after the mass was resected. Conclusion: Renin-secreting ovarian adult granulosa cell tumors are rare causes of hyperreninemia leading to hypertension and hypokalemia.

AB - Objective: To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia. Methods: We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor. Results: A 31-year-old female presented with hypertension and amenorrhea. She was found to have spontaneous hypokalemia. Computed tomography scan showed a pelvic mass which was resected and found to be a renin-secreting ovarian adult granulosa cell tumor. The hypertension and hypokalemia resolved after the mass was resected. Conclusion: Renin-secreting ovarian adult granulosa cell tumors are rare causes of hyperreninemia leading to hypertension and hypokalemia.

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Renin-Secreting Ovarian Adult Granulosa Cell Tumor in a Patient With New-Onset Hypertension and Hypokalemia

Abstract

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