Rhegmatogenous Retinal Detachment in Patients with Acute Syphilitic Panuveitis

Sara J. Haug, Ako Takakura, J. Michael Jumper, David Heiden, H. Richard McDonald, Robert N. Johnson, Arthur D. Fu, Brandon J. Lujan, Emmett T. Cunningham

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Purpose: To describe the clinical characteristics and surgical management of rhegmatogenous retinal detachment (RD) in patients with acute syphilitic panuveitis. Methods: Retrospective case series and comprehensive literature review. Results: Including present and previously reported cases, we identified 11 eyes in 8 patients with acute syphilitic panuveitis that developed a rhegmatogenous RD. Seven of 11 eyes (63.6%) were repaired with a combined scleral buckling, vitrectomy, and endolaser photocoagulation surgery; 1 eye (9.1%) was repaired with scleral buckling only; and 2 eyes (18.2%) with vitrectomy only. Cryotherapy was used to treat a giant retinal tear in 1 eye (9.1%). Four eyes (36.4%) redetached and 3 underwent a second vitrectomy surgery. Conclusions: Although uncommon, rhegmatogenous RD can occur in patients with moderate to severe acute syphilitic panuveitis. We believe scleral buckling, vitrectomy, endolaser photocoagulation, and silicone oil tamponade give the best chance for successful retinal reattachment.

Original languageEnglish (US)
Pages (from-to)69-76
Number of pages8
JournalOcular Immunology and Inflammation
Issue number1
StatePublished - Jan 2 2016
Externally publishedYes


  • Giant retinal tear
  • lues
  • proliferative vitreoretinopathy
  • retina detachment
  • retinitis
  • syphilis
  • uveitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology


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