TY - JOUR
T1 - Ripping and stitching with copper
AU - Blackburn, Ninian J.
N1 - Publisher Copyright:
© Springer Nature America, Inc. 2024.
PY - 2024/4
Y1 - 2024/4
N2 - BURP-domain proteins belong to an emerging class of autocatalytic copper-containing proteins that modify themselves after synthesis. Now, a report explains how their structure and metal coordination sphere control the installation of crosslinks within the core peptide, and shows how nature leverages mechanistic paradigms to create diversity.
AB - BURP-domain proteins belong to an emerging class of autocatalytic copper-containing proteins that modify themselves after synthesis. Now, a report explains how their structure and metal coordination sphere control the installation of crosslinks within the core peptide, and shows how nature leverages mechanistic paradigms to create diversity.
UR - http://www.scopus.com/inward/record.url?scp=85188447677&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85188447677&partnerID=8YFLogxK
U2 - 10.1038/s41589-024-01582-9
DO - 10.1038/s41589-024-01582-9
M3 - Comment/debate
C2 - 38514883
AN - SCOPUS:85188447677
SN - 1552-4450
VL - 20
SP - 404
EP - 405
JO - Nature Chemical Biology
JF - Nature Chemical Biology
IS - 4
ER -