RNA trafficking in myelinating cells

John H. Carson; Sunjong Kwon; Elisa Barbarese

doi:10.1016/S0959-4388(98)80088-3

RNA trafficking in myelinating cells

John H. Carson, Sunjong Kwon, Elisa Barbarese

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

Abstract

In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRNA; hnRNP A2 has been identified as a trans-acting factor in oligodendrocytes that binds specifically to the RNA transport sequence; and microtubules and kinesin have been identified as cytoskeletal elements required for RNA transport in oligodendrocytes.

Original language	English (US)
Pages (from-to)	607-612
Number of pages	6
Journal	Current Opinion in Neurobiology
Volume	8
Issue number	5
DOIs	https://doi.org/10.1016/S0959-4388(98)80088-3
State	Published - Oct 1998
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/S0959-4388(98)80088-3

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@article{2f111ca1d0d441bba1816f1753c72046,

title = "RNA trafficking in myelinating cells",

abstract = "In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRNA; hnRNP A2 has been identified as a trans-acting factor in oligodendrocytes that binds specifically to the RNA transport sequence; and microtubules and kinesin have been identified as cytoskeletal elements required for RNA transport in oligodendrocytes.",

author = "Carson, {John H.} and Sunjong Kwon and Elisa Barbarese",

note = "Funding Information: The authorsa cknowledges upport from National Institutes of Health grants NS15190 to JH Carson and NSlYY43 to E Barbarese, and from the National Multiple SclerosisS ociety grant RGZ843-A-2 toE Barharcse:",

year = "1998",

month = oct,

doi = "10.1016/S0959-4388(98)80088-3",

language = "English (US)",

volume = "8",

pages = "607--612",

journal = "Current Opinion in Neurobiology",

issn = "0959-4388",

publisher = "Elsevier Limited",

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TY - JOUR

T1 - RNA trafficking in myelinating cells

AU - Carson, John H.

AU - Kwon, Sunjong

AU - Barbarese, Elisa

N1 - Funding Information: The authorsa cknowledges upport from National Institutes of Health grants NS15190 to JH Carson and NSlYY43 to E Barbarese, and from the National Multiple SclerosisS ociety grant RGZ843-A-2 toE Barharcse:

PY - 1998/10

Y1 - 1998/10

N2 - In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRNA; hnRNP A2 has been identified as a trans-acting factor in oligodendrocytes that binds specifically to the RNA transport sequence; and microtubules and kinesin have been identified as cytoskeletal elements required for RNA transport in oligodendrocytes.

AB - In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRNA; hnRNP A2 has been identified as a trans-acting factor in oligodendrocytes that binds specifically to the RNA transport sequence; and microtubules and kinesin have been identified as cytoskeletal elements required for RNA transport in oligodendrocytes.

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DO - 10.1016/S0959-4388(98)80088-3

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SN - 0959-4388

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EP - 612

JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

IS - 5

ER -

RNA trafficking in myelinating cells

Abstract

ASJC Scopus subject areas

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