Role of infiltrated leucocytes in tumour growth and spread

E. Y. Lin, J. W. Pollard

Research output: Contribution to journalShort surveypeer-review

218 Scopus citations


Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis.

Original languageEnglish (US)
Pages (from-to)2053-2058
Number of pages6
JournalBritish Journal of Cancer
Issue number11
StatePublished - Jun 1 2004
Externally publishedYes


  • Angiogenesis
  • Leucocyte
  • Metastasis
  • Progression
  • Tumour

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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