Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Goksemin Acar; Feridun Acar; Jonathan Miller; David C. Spencer; Kim J. Burchiel

doi:10.1159/000160154

Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Goksemin Acar, Feridun Acar, Jonathan Miller, David C. Spencer, Kim J. Burchiel

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28 Scopus citations

Abstract

The aim of this study was to retrospectively determine if patients with medically refractory epilepsy, due to hippocampal sclerosis, who underwent selective amygdalohippocampectomy (SAH) with a transcortical approach experienced improved seizure outcome. Thirty-nine patients with mesial temporal lobe epilepsy and hippocampal sclerosis were included in the study. The mean follow-up was 25.88 ± 17.69 months. Antiepileptic medication use and seizure frequency were significantly reduced after SAH. After surgery, 32 patients (82.05%) were completely seizure free (Engel class IA), and 2 patients experienced transient memory difficulty. In conclusion, SAH with a transcortical approach can lead to favorable seizure control with a low irreversible complication risk.

Original language	English (US)
Pages (from-to)	314-319
Number of pages	6
Journal	Stereotactic and Functional Neurosurgery
Volume	86
Issue number	5
DOIs	https://doi.org/10.1159/000160154
State	Published - Oct 2008

Keywords

Hippocampal sclerosis
Mesial temporal lobe epilepsy
Seizure outcome
Selective amygdalohippocampectomy, transcortical

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1159/000160154

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title = "Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy",

abstract = "The aim of this study was to retrospectively determine if patients with medically refractory epilepsy, due to hippocampal sclerosis, who underwent selective amygdalohippocampectomy (SAH) with a transcortical approach experienced improved seizure outcome. Thirty-nine patients with mesial temporal lobe epilepsy and hippocampal sclerosis were included in the study. The mean follow-up was 25.88 ± 17.69 months. Antiepileptic medication use and seizure frequency were significantly reduced after SAH. After surgery, 32 patients (82.05%) were completely seizure free (Engel class IA), and 2 patients experienced transient memory difficulty. In conclusion, SAH with a transcortical approach can lead to favorable seizure control with a low irreversible complication risk.",

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AU - Miller, Jonathan

AU - Spencer, David C.

AU - Burchiel, Kim J.

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Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Abstract

Keywords

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