@inbook{73885881472d451db3758257b9c28e06,
title = "Sex differences in androgen regulation of metabolism in nonhuman primates",
abstract = "The in-depth characterization of sex differences relevant to human physiology requires the judicious use of a variety of animal models and human clinical data. Nonhuman primates (NHPs) represent an important experimental system that bridges rodent studies and clinical investigations. NHP studies have been especially useful in understanding the role of sex hormones in development and metabolism and also allow the elucidation of the effects of pertinent dietary influences on physiology pertinent to disease states such as obesity and diabetes. This chapter summarizes the current state of our understanding of androgen effects on male and female NHP metabolism relevant to hypogonadism in human males and polycystic ovary syndrome in human females. This review will also focus on the interaction between altered androgen levels and dietary restriction and excess, in particular the Westernstyle diet that underlies significant human pathophysiology.",
author = "Cadence True and Abbott, {David H.} and Roberts, {Charles T.} and Oleg Varlamov",
note = "Funding Information: The authors would like to acknowledge their funding support from Eunice Kennedy Shriver National Institute of Child Health & Human Development P50 HD071836. The content is solely the responsibility of the authors and does not necessarily represent the off ial views of the National Institutes of Health. This work was also supported by NIH grants P51 OD011092 for operation of the Oregon National Primate Research Center, P51 OD011106 for operation of the Wisconsin National Primate Research Center, R01 RR013635, P50 HD044405, and R21 AG047543. Publisher Copyright: {\textcopyright} Springer International Publishing AG 2017.",
year = "2017",
doi = "10.1007/978-3-319-70178-3_24",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "559--574",
booktitle = "Advances in Experimental Medicine and Biology",
}