Single unit recordings in the rat pineal gland: Evidence for habenulo-pineal neural connections

O. K. Rønnekleiv; M. J. Kelly; W. Wuttke

doi:10.1007/BF00237549

Single unit recordings in the rat pineal gland: Evidence for habenulo-pineal neural connections

O. K. Rønnekleiv, M. J. Kelly, W. Wuttke

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Extracellular potentials were recorded in the pineal gland of urethane-anesthetized rats. Two distinct populations of excitable pineal "cells" were found, the silent "cells" which were driven by habenula stimulation and the spontaneously active cells. In the former case 17 of the responses (median latency of 1.2 ms) showed a positive-negative potential, and 6 (about 1 ms latency) showed only positive potential of 1-2 ms duration. The remaining cells (114), which could not be driven by habenula stimulation, exhibited spontaneous activity with a firing frequency from less than 1 Hz to greater than 100 Hz with a median firing frequency of 10 Hz. These experiments clearly demonstrate a direct habenulo-pineal fiber pathway and furthermore show that there are neuronal elements in the pineal which are only activated by habenula stimulation.

Original language	English (US)
Pages (from-to)	187-192
Number of pages	6
Journal	Experimental Brain Research
Volume	39
Issue number	2
DOIs	https://doi.org/10.1007/BF00237549
State	Published - May 1980
Externally published	Yes

Keywords

Habenula stimulation
Habenulo-pineal pathway
Pineal
Single unit recording

ASJC Scopus subject areas

Neuroscience(all)

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10.1007/BF00237549

Cite this

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title = "Single unit recordings in the rat pineal gland: Evidence for habenulo-pineal neural connections",

abstract = "Extracellular potentials were recorded in the pineal gland of urethane-anesthetized rats. Two distinct populations of excitable pineal {"}cells{"} were found, the silent {"}cells{"} which were driven by habenula stimulation and the spontaneously active cells. In the former case 17 of the responses (median latency of 1.2 ms) showed a positive-negative potential, and 6 (about 1 ms latency) showed only positive potential of 1-2 ms duration. The remaining cells (114), which could not be driven by habenula stimulation, exhibited spontaneous activity with a firing frequency from less than 1 Hz to greater than 100 Hz with a median firing frequency of 10 Hz. These experiments clearly demonstrate a direct habenulo-pineal fiber pathway and furthermore show that there are neuronal elements in the pineal which are only activated by habenula stimulation.",

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AU - Rønnekleiv, O. K.

AU - Kelly, M. J.

AU - Wuttke, W.

PY - 1980/5

Y1 - 1980/5

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Single unit recordings in the rat pineal gland: Evidence for habenulo-pineal neural connections

Abstract

Keywords

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