Abstract
Monocular enucleation at E36, followed by intracellular labeling of single, physiologically identified X and Y axons, demonstrates fundamental differences in their termination patterns within the lateral geniculate nucleus (LGN). X axons have arbors that appear normal in their dorsoventral extent, though some are located in inappropriate regions of the LGN. Y axons have arbors that are either abnormally tall, spanning the entire extent of the LGN, or of normal height but located in inappropriate regions of the LGN. These termination patterns resemble patterns seen after monocular enucleation at E44, and reinforce the conclusion that X and Y axons differ fundamentally in the cues that constrain the dorsoventral extents of their arbors.
Original language | English (US) |
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Pages (from-to) | 227-231 |
Number of pages | 5 |
Journal | Developmental Brain Research |
Volume | 107 |
Issue number | 2 |
DOIs | |
State | Published - May 15 1998 |
Externally published | Yes |
Keywords
- Binocular competition
- Lateral geniculate nucleus
- Retinogeniculate development
ASJC Scopus subject areas
- Developmental Neuroscience
- Developmental Biology