Sultam thioureas: Synthesis and antiviral activity against west nile virus

Rachel M. Feeny, Diane N. Le, Joseph W. Parks, Mark G. Epstein, Joseph V. Pagano, Albert C. Abbene, Elaina B. Graham, Joanna R. Farrell, Jason R. McGuire, Robert W. Zoellner, Edward J. Valente, Eric Barklis, Warren J.L. Wood

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The syntheses of eleven sultam thioureas, including nine new compounds, are described. These compounds were synthesized from thioureas and include the first sultam thioureas in which the two thiourea nitrogen groups are not identical. In addition, the first X-ray crystal structures of sultam thioureas and the antiviral activity of these compounds against West Nile virus (WNV) are reported.

Original languageEnglish (US)
Pages (from-to)301-305
Number of pages5
Issue number2
StatePublished - 2012


  • West Nile virus
  • antiviral agents
  • heterocycles
  • medicinal chemistry
  • sultam thioureas
  • thioureas

ASJC Scopus subject areas

  • Organic Chemistry


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