TY - JOUR
T1 - Tachycardia-induced cardiomyopathy secondary to incessant ectopic atrial tachycardia in two infants
T2 - Potential new indication for early initiation of enteral ivabradine
AU - Karmegaraj, Balaganesh
AU - Balaji, Seshadri
AU - Raju, Prasanna
AU - Subramanian, Pradheep
AU - Subramanian, Raju
AU - Ibrahim, Syed
AU - Razeen, Mohamed
AU - Krishnakumar, Raman
N1 - Publisher Copyright:
© 2021 Wolters Kluwer Medknow Publications. All rights reserved.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - This report describes two cases of tachycardia-induced cardiomyopathy secondary to incessant ectopic atrial tachycardia (EAT) in an infant presenting with severe left ventricular dysfunction and hemodynamic instability. The two cases were managed differently. The first required mechanical ventilation and was resistant to conventional antiarrhythmic drugs. After the initiation of enteral ivabradine (0.15mg/kg) the heart rate slowed with significant improvement in hemodynamics, peripheral perfusion and sinus rhythm was restored after 12 hours. Ivabradine was continued and the patient was discharged home after 10 days of hospitalization. The second case was managed by early initiation of ivabradine and resulted in restoration of sinus rhythm within 4 hours, thus avoiding trials of conventional anti-arrhythmic drugs with unstable hemodynamic profile. The infant was discharged after 5 days of hospitalization on ivabradine..
AB - This report describes two cases of tachycardia-induced cardiomyopathy secondary to incessant ectopic atrial tachycardia (EAT) in an infant presenting with severe left ventricular dysfunction and hemodynamic instability. The two cases were managed differently. The first required mechanical ventilation and was resistant to conventional antiarrhythmic drugs. After the initiation of enteral ivabradine (0.15mg/kg) the heart rate slowed with significant improvement in hemodynamics, peripheral perfusion and sinus rhythm was restored after 12 hours. Ivabradine was continued and the patient was discharged home after 10 days of hospitalization. The second case was managed by early initiation of ivabradine and resulted in restoration of sinus rhythm within 4 hours, thus avoiding trials of conventional anti-arrhythmic drugs with unstable hemodynamic profile. The infant was discharged after 5 days of hospitalization on ivabradine..
KW - Ectopic atrial tachycardia
KW - infant
KW - ivabradine
KW - tachycardia-induced cardiomyopathy
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U2 - 10.4103/apc.apc_37_21
DO - 10.4103/apc.apc_37_21
M3 - Article
AN - SCOPUS:85114493833
SN - 0974-2069
VL - 14
SP - 422
EP - 427
JO - Annals of Pediatric Cardiology
JF - Annals of Pediatric Cardiology
IS - 3
ER -