The cost of necrotizing enterocolitis in premature infants

Meredith E. Mowitz, Dmitry Dukhovny, John A.F. Zupancic

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations


Necrotizing enterocolitis (NEC), a common morbidity of prematurity, affects 5–10% of premature infants with a birthweight <1500 g. The added cost remains unclear. Multiple studies report the cost of care for an infant with NEC as higher than that of well premature infants, but these studies are fraught with limitations. Surgical intervention and type of surgery appear to impact overall costs. Health care resource utilization extends beyond the birth hospitalization, particularly in those infants requiring surgery, and persists to at least three years of age. This narrative review of the literature reveals a paucity of studies and significant methodological deficiencies in most included studies. Further studies of the cost of NEC need to address the issues of significant confounding in this complex population.

Original languageEnglish (US)
Pages (from-to)416-419
Number of pages4
JournalSeminars in Fetal and Neonatal Medicine
Issue number6
StatePublished - Dec 2018


  • Costs
  • Necrotizing enterocolitis
  • Premature infant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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