TY - JOUR
T1 - The Debate about n-6 Polyunsaturated Fatty Acid Recommendations for Cardiovascular Health
AU - Kris-Etherton, Penny
AU - Fleming, Jennifer
AU - Harris, William S.
PY - 2010/2
Y1 - 2010/2
N2 - The ongoing debate about n-6 fatty acid recommendations was the impetus for the AHA Science Advisory that framed the cardiovascular benefits of a diet that provides 5% to 10% of energy from n-6 PUFA (3). The voice of opposition to this recommendation has built their argument on the hypothesis that LA adversely affects inflammation by increasing pro-inflammatory metabolites. However, based on a large and impressive evidence base, n-6 PUFA reduces risk of CHD. Thus, planning diets that meet current recommendations for n-6 PUFA and include all other recommendations for heart health (19) (eg, reducing SFA, trans-fatty acids, and sodium, as well as increasing dietary fiber) will achieve the greatest benefit of diet on reducing cardiovascular disease risk. As summarized herein, different strategies are presented to meet fatty acid recommendations that increase n-6 PUFA and decrease SFA, decrease SFA and maintain PUFA, and increase n-6 PUFA in diets that provide less than 5% of energy.
AB - The ongoing debate about n-6 fatty acid recommendations was the impetus for the AHA Science Advisory that framed the cardiovascular benefits of a diet that provides 5% to 10% of energy from n-6 PUFA (3). The voice of opposition to this recommendation has built their argument on the hypothesis that LA adversely affects inflammation by increasing pro-inflammatory metabolites. However, based on a large and impressive evidence base, n-6 PUFA reduces risk of CHD. Thus, planning diets that meet current recommendations for n-6 PUFA and include all other recommendations for heart health (19) (eg, reducing SFA, trans-fatty acids, and sodium, as well as increasing dietary fiber) will achieve the greatest benefit of diet on reducing cardiovascular disease risk. As summarized herein, different strategies are presented to meet fatty acid recommendations that increase n-6 PUFA and decrease SFA, decrease SFA and maintain PUFA, and increase n-6 PUFA in diets that provide less than 5% of energy.
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U2 - 10.1016/j.jada.2009.12.006
DO - 10.1016/j.jada.2009.12.006
M3 - Article
C2 - 20102846
AN - SCOPUS:74549128191
SN - 0002-8223
VL - 110
SP - 201
EP - 204
JO - Journal of the American Dietetic Association
JF - Journal of the American Dietetic Association
IS - 2
ER -