TY - JOUR
T1 - The effect of ophthalmic ointments on corneal wound healing
AU - Hanna, Calvin
AU - Fraunfelder, Frederick T.
AU - Cable, Melanie
AU - Hardberger, Rufus E.
N1 - Funding Information:
From the Departments of Ophthalmology and Pharmacology, University of Arkansas Medical Center, Little Rock. This work was supported in part by Public Health Service Research Grants EY-00059, 00270, 00239, and 00891 from the National Institutes of Health and by a grant from Research to Prevent Blindness, Inc.
PY - 1973/8
Y1 - 1973/8
N2 - The corneas of rats, rabbits, and monkeys were wounded and ophthalmic ointments immediately applied. The rate of re-epithelization of corneal abrasions or healing of keratectomies with or without the application of commercial ointments was measured. The various non-emulsive ointments bases included white petrolatum or mineral oil with or without lanolin. In addition, some ointments contained antibiotics, anti-inflammatory corticosteroid, boric acid, and preservatives. There was no evidence to indicate that current ophthalmic ointments alone or in combinations with the ophthalmic drugs tested interfered with corneal wound healing.
AB - The corneas of rats, rabbits, and monkeys were wounded and ophthalmic ointments immediately applied. The rate of re-epithelization of corneal abrasions or healing of keratectomies with or without the application of commercial ointments was measured. The various non-emulsive ointments bases included white petrolatum or mineral oil with or without lanolin. In addition, some ointments contained antibiotics, anti-inflammatory corticosteroid, boric acid, and preservatives. There was no evidence to indicate that current ophthalmic ointments alone or in combinations with the ophthalmic drugs tested interfered with corneal wound healing.
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U2 - 10.1016/0002-9394(73)90159-1
DO - 10.1016/0002-9394(73)90159-1
M3 - Article
C2 - 4353441
AN - SCOPUS:0015798843
SN - 0002-9394
VL - 76
SP - 193
EP - 200
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 2
ER -