The ORF61 protein encoded by Simian varicella virus and Varicella-zoster virus inhibits NF-κB signaling by interfering with IκBα degradation

Agriculture & Biology

• Cercopithecine alphaherpesvirus 9 100%
• Human alphaherpesvirus 3 78%
• degradation 31%
• proteins 17%
• ubiquitination 16%
• infection 13%
• phosphorylation 11%
• immune evasion 9%
• viruses 8%
• interferons 7%
• ubiquitin 7%
• protein degradation 6%
• tumor necrosis factor-alpha 6%
• crossover interference 6%
• Macaca mulatta 6%
• innate immunity 6%
• ligases 6%
• cytokines 6%
• snails 6%
• pathogenesis 5%
• transcription factors 4%

Medicine & Life Sciences

• Human Herpesvirus 3 63%
• Chickenpox 62%
• Viruses 34%
• Proteins 18%
• Varicella-zoster virus protein 61 11%
• SKP Cullin F-Box Protein Ligases 8%
• Virus Diseases 7%
• Postherpetic Neuralgia 7%
• Phosphorylation 7%
• Immune Evasion 6%
• Herpes Zoster 5%
• Ectopic Gene Expression 5%
• Macaca mulatta 5%
• Ganglia 5%
• Infections 4%
• Proteolysis 4%
• Innate Immunity 4%
• Interferons 4%
• Transcription Factors 3%
• Tumor Necrosis Factor-alpha 3%
• Cytokines 3%